Brain stimulation offers hope for depression, but don't try it at home

Posted on December 8, 2014

Photo: flickr

In search of alternative solutions, researchers around the world, including our team, are investigating transcranial direct current stimulation (TDCS) as an alternative treatment for depression. But this isn’t something you can safely try at home.

Unlike electroconvulsive therapy, TDCS uses very mild electric current to stimulate the brain and has few side effects. The mechanics of TDCS are quite simple, involving a battery, two leads and the electrodes through which the current is passed.

The stimulation works by changing the activity of nerve cells in the brain. In depression, the left frontal areas of the brain are often less active than usual. TDCS stimulates this area to restore brain activity.

We’re still evaluating the effectiveness of TDCS, but so far studies have found that TDCS works better than a placebo (or simulated treatment) at reducing symptoms of depression.

When combined with the antidepressant medication sertraline (marketed as Zoloft in Australia), the combination TDCS-drug therapy works better than medication or TDCS alone.

Research has found that among people with depression, a course of TDCS can improve the brain’s “neuroplasticity”, which is the brain’s ability to learn and adapt to changes in the environment.

The therapy has a good safety profile – if administered by clinicians and researchers trained in stimulation technique and safety. Our research team has administered thousands of TDCS sessions without incident.

But this is not the case when TDCS is used in the “DIY” context, with DIY users trying to stimulate their own brains.

This phenomenon is often guided by online forums and websites dedicated to DIY TDCS. Users comment on their own experience and share tips on how TDCS can be used to treat their own depression. People with no medical training and limited understanding of TDCS self-treat their depression and advise others on treatment.

So, what can go wrong?
The most obvious concern is that poor technique and improper electrode placement could cause skin burns.

What’s more concerning is the ability for TDCS to produce lasting changes in brain functioning. Depending on how TDCS is given, these changes could be good or bad.

TDCS represents a promising future, where simple and cost-effective treatment for depression is possible, without drugs. Researchers worldwide are continuing to study this experimental treatment, which may one day become a conventional treatment for depression.

The acceptance and popularity of TDCS among the general community is encouraging. But TDCS is still experimental and isn’t safe to administer at home. DIY users are not trained in proper technique nor are they trained to identify, prevent or deal with unexpected outcomes.


Category(s):Depression

Source material from The Conservation