Social Anxiety Linked To Surprise Chemical Imbalance In The Brain

Posted on June 22, 2015

Drugs commonly prescribed for social anxiety could be making the problem worse. Social anxiety disorder is linked to higher levels of serotonin in the brain, not lower as previously thought. People with both social anxiety actually produce more of the neurotransmitter serotonin in their brains. The more serotonin they produce, the more anxious they become.
The result is a surprise as social anxiety are often treated with SSRIs like Prozac, Paxil and Zoloft. SSRIs actually increase the levels of serotonin in the brain.

Mr Andreas Frick, the study’s first author, said:
“Not only did individuals with social phobia make more serotonin than people without such a disorder, they also pump back more serotonin. We were able to show this in another group of patients using a different tracer which itself measures the pump mechanism. We believe that this is an attempt to compensate for the excess serotonin active in transmitting signals.”

For the study, 18 people with social anxiety disorder had the serotonin levels measured in their brains. These were compared to people without the disorder.

Mr Frick said:
“Serotonin can increase anxiety and not decrease it as was previously often assumed.”

The findings follow on studies questioning the link between depression and low serotonin.

The research was published in the journal JAMA Psychiatry (Frick et al., 2015).

To read the full article, click on the link below.

Category(s):Social Anxiety / Phobia

Source material from Journal of the American Medical Association