Early life stress can leave lasting impacts on the brain

Posted on July 2, 2014

For children, stress can go a long way. A little bit provides a platform for learning, adapting and coping. But a lot of it - chronic, toxic stress like poverty, neglect and physical abuse - can have lasting negative impacts.

A team of University of Wisconsin-Madison researchers recently showed these kinds of stressors, experienced in early life, might be changing the parts of developing children's brains responsible for learning, memory and the processing of stress and emotion. These changes may be tied to negative impacts on behavior, health, employment and even the choice of romantic partners later in life.

"We haven't really understood why things that happen when you're 2, 3, 4 years old stay with you and have a lasting impact," says Seth Pollak, co-leader of the study and UW-Madison professor of psychology.

Yet, early life stress has been tied before to depression, anxiety, heart disease, cancer, and a lack of educational and employment success, says Pollak, who is also director of the UW Waisman Center's Child Emotion Research Laboratory.

"Given how costly these early stressful experiences are for society ... unless we understand what part of the brain is affected, we won't be able to tailor something to do about it," he says.

For the study, the team recruited 128 children around age 12 who had experienced either physical abuse, neglect early in life or came from low socioeconomic status households.

Researchers conducted extensive interviews with the children and their caregivers, documenting behavioral problems and their cumulative life stress. They also took images of the children's brains, focusing on the hippocampus and amygdala, which are involved in emotion and stress processing. They were compared to similar children from middle-class households who had not been maltreated.

Hanson and the team outlined by hand each child's hippocampus and amygdala and calculated their volumes. Both structures are very small, especially in children (the word amygdala is Greek for almond, reflecting its size and shape in adults), and Hanson and Pollak say the automated software measurements from other studies may be prone to error.

Indeed, their hand measurements found that children who experienced any of the three types of early life stress had smaller amygdalas than children who had not. Children from low socioeconomic status households and children who had been physically abused also had smaller hippocampal volumes. Putting the same images through automated software showed no effects.

Behavioral problems and increased cumulative life stress were also linked to smaller hippocampus and amygdala volumes.

"For me, it's an important reminder that as a society we need to attend to the types of experiences children are having," Pollak says. "We are shaping the people these individuals will become."


Category(s):Child Development, Stress Management

Source material from University of Wisconsin-Madison


Mental Health News

  • Forgiveness and Emotional Freedom

    newsthumbThis article talks about how showing forgiveness is the best route to emotional healing and freedom.

  • Advantages of being Narcissistic

    newsthumbNarcissism has a negative connotation and is often seen as an undesirable trait to have. However, recent findings show that there are positive ...

  • Diving into Emotional Abuse

    newsthumbThere are often certain misconceptions and misunderstandings about the definition of Emotional Abuse and the effects that come with it. This article ...