Gaining new knowledge alters brain cells

Posted on February 27, 2014

A new University of British Columbia study identifies an important molecular change that occurs in the brain when we learn and remember.

Published this month in Nature Neuroscience, the research shows that learning stimulates our brain cells in a manner that causes a small fatty acid to attach to delta-catenin, a protein in the brain. This biochemical modification is essential in producing the changes in brain cell connectivity associated with learning, the study finds.

"More work is needed, but this discovery gives us a much better understanding of the tools our brains use to learn and remember, and provides insight into how these processes become disrupted in neurological diseases," says co-author Shernaz Bamji, an associate professor in UBC’s Life Sciences Institute.

"Brain activity can change both the structure of this protein, as well as its function," says Stefano Brigidi, first author of the article and a PhD candidate Bamji's laboratory. "When we introduced a mutation that blocked the biochemical modification that occurs in healthy subjects, we abolished the structural changes in brain's cells that are known to be important for memory formation."


Source material from University of British Columbia


Mental Health News

  • Forgiveness and Emotional Freedom

    newsthumbThis article talks about how showing forgiveness is the best route to emotional healing and freedom.

  • Advantages of being Narcissistic

    newsthumbNarcissism has a negative connotation and is often seen as an undesirable trait to have. However, recent findings show that there are positive ...

  • Diving into Emotional Abuse

    newsthumbThere are often certain misconceptions and misunderstandings about the definition of Emotional Abuse and the effects that come with it. This article ...