Exposure/ritual prevention therapy boosts antidepressant treatment of OCD

Posted on September 20, 2013

NIMH grantees have demonstrated that a form of behavioral therapy can augment antidepressant treatment of obsessive compulsive disorder (OCD) better than an antipsychotic. The researchers recommend that this specific form of cognitive behavior therapy (CBT) - exposure and ritual prevention - be offered to OCD patients who don't respond adequately to treatment with an antidepressant alone, which is often the case. Current guidelines favor augmentation with antipsychotics.

In the controlled trial with 100 antidepressant-refractory OCD patients, 80 percent of those who received CBT responded, compared to 23 percent of those who received the antipsychotic risperidone, and 15 percent of those who received placebo pills. Forty-three percent experienced symptoms reduced to a minimal level following CBT treatment, compared to 13 percent for risperidone and 5 percent for placebo.


Category(s):Obsessions & Compulsions (OCD)

Source material from MND


Mental Health News

  • To what extent is it Emotional Abuse?

    newsthumbThis article helps us identify what is deemed as emotional abuse, when and how is an action or situation a form of emotional abuse.

  • Inequality as a disorder

    newsthumbEconomic inequality is one of the signs that foreshadows societal disorder. It can also negatively impact people’s lives and is highly associated ...

  • The Truth about Psychopaths

    newsthumbThis article talks about the common misconceptions people have about psychopaths and who they really are, what type of person they are and what drew ...